Evaluation of Antimicrobial and Structural Properties of Thyme Essential Oil-Loaded Chitosan-Capric Acid and Chitosan-Stearic Acid Nanogels
نویسندگان
1 Department of Food Science, Nutrition and Clinical Biochemistry, School of Medicine, Gonabad University of Medical Sciences, Gonabad, Iran, Research Center for Food Hygiene and Safety, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
2 Nanotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran, Pharmaceutics Department, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Biopathology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran, Pharmaceutical Control Department, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
4 Department of Applied Sciences, College of Applied Sciences and Pharmacy, University of Technology and Applied Sciences, Muscat, Oman
5 Department of Food Science and Technology, University of Shahrood, Shahrood, Iran
6 Department of Chemical Engineering, Chungbuk National University, Cheongju, Chungbuk 28644, Republic of Korea
7 Department of Biopathology, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran, Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran
8 Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran, Targeted Drug Delivery Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran
doi
10.18502/jfqhc.10.3.13646چکیده
Background: This study aimed to investigate the physicochemical properties, antimicrobial activity, and cytotoxicity of Thyme Essential Oil (TEO) encapsulated by chitosan nanogels. Methods: In this study, chitosan-stearic acid and chitosan-capric acid nanogels were developed in two ratios of chitosan to fatty acid (10: 1 and 10: 3). Results: The results of ...