Detection of FLT3 Gene Mutations In Patients With Acute Myeloid Leukemia In Surabaya, Indonesia: A Single-Center Study

نویسندگان
Jusak, Nugraha ID 1
Notopuro, Paulus Budiono ID 2
Harianto, Notopuro ID 3

1 Departement of Clinical Pathology, Faculty of Medicine Airlangga University, Surabaya, Indonesia

2 Doctoral Student, Faculty of Medicine, Airlangga University, Indonesia

3 Departement of Biochemistry, Faculty of Medicine Airlangga University, Surabaya, Indonesia

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چکیده

Background:  FLT3 gene mutation contributes worse prognosis in patients with acute myeloid leukemia (AML). Almost 67% of patients with AML with FLT3 gene mutation cannot reach complete remission after induction therapy, and  they are also at high risk of  relapse. We aimed to investigate the FLT3-ITD, -TKD (D835) gene mutation ...

کلیدواژه‌ها
Acute myeloid leukemia, Leukocyte, Blast count, FLT3-ITD, FLT3-TKD (D835)