In Silico Activity of AS1411 Aptamer Against Nucleolin of Cancer Cells

نویسندگان
Farahbakhsh, Zohreh ID 1
Gulseren, Oguz ID 2
Zamani, Mohammad Reza ID 3
Rafienia, Mohammad ID 4
Mirzaei, Mahmoud ID 5

1 NourDanesh Institute of Higher Education, Meymeh, Iran

2 Deaprtment of Physics, Bilkent University, Ankara,

3 National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

4 Biosensor Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

5 Biosensor Research Center, School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

doi
چکیده

Background: It has been expected that AS1411 aptamer could work against the cancer cells. Although the general information is available, there is still lack of details for the purpose. Therefore, activity of AS1411 aptamer against the nucleolin (NCL) target of cancer cells has been investigated in current work at the ...

کلیدواژه‌ها
Aptamer, AS1411, AT11, Nucleolin, In Silico