Prevalence of primary osteoporosis and low bone mass in postmenopausal women and related risk factors
نویسندگان
1 Nutrition Research Center, Tabriz University of Medical Sciences, Tabriz, Iran, Department of Midwifery, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, Iran
2 Physical Medicine and Rehabilitation Research Centre, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
3 , Bone Densitometry Center, Sina Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
4 Physical Medicine and Rehabilitation Research Centre, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
5 Social Determinants of Health Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
6 Endocrine Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
doi
چکیده
BACKGROUND: Globally, 30% of female over 50 years old have osteoporosis. This disease is oneof the major causes of disability and death in the elderly. This research was aimed to determinethe prevalence of primary osteoporosis and low bone density based on bone mineral density inpostmenopausal women and its sociodemographic, obstetric, and life style risk factors.MATERIALS AND METHODS: This cross-sectional descriptive-analytical study was performed bysimple random sampling on 850 postmenopausal women aged 50–65 years covered by all healthcenters, from August 2018 to April 2019, in Tabriz-Iran. Four hundred and forty-five eligible womenunderwent densitometry using dual-energy X-ray absorptiometry in the lumbar spine and femoralneck. Socio-individual, obstetric-medical, international physical activity questionnaires-short form,and anthropometric questionnaires were completed. Data analyzed using descriptive and analyticalstatistics including multivariate logistic regression in SPSS 21 software.RESULTS: The prevalence of primary osteoporosis based on lumbar vertebra T-score, femoralneck T-score, and total was 23.4%, 3.4%, and 24.5%, respectively, and the prevalence of primaryosteopenia based on lumbar vertebra T-score, femur neck T-score, and total was 42%, 35.5%, and43.6%, respectively. The present study showed that the odds of osteoporosis increased by incrementof age (odds ratio [OR]: 1.18; 95% confidence interval [CI]: 1.07–1.30), but it decreased by increasingmenopausal age (OR: 0.92; 95% CI: 0.85–1.01), body mass index (OR: 0.87; 95% CI: 0.78–0.97),arm circumference (OR: 0.84; 95% CI: 0.74–0.95), and education level (P = 0.028). It was higher inunmarried women (OR: 2.65; 95% CI: 0.99–7.08) and those with nonpersonal housing (OR: 4.02;95% CI: 1.24–13.07).CONCLUSIONS: Given the high prevalence of primary osteoporosis and low bone mass in postmenopausalwomen, health education is necessary for preventing modifiable risk factors and reducing the complicationsof this disease.
