Flow Cytometry-based Functional Assay is a Valuable Diagnostic Approach for Confirmation of Heparin-Induced Thrombocytopenia

نویسندگان
Norouzi, Mahshaad ID 1
Balagholi, Sahar ID 2
Teimourpour, Amir ID 3
Ahmadinejad, Minoo ID 4

1 Blood Transfusion Research Center, High Institute for Education and Research in Transfusion Medicine, Tehran, Iran.

2 Blood Transfusion Research Center, High Institute for Education and Research in Transfusion Medicine, Tehran, Iran.

3 Blood Transfusion Research Center, High Institute for Education and Research in Transfusion Medicine, Tehran, Iran.

4 Blood Transfusion Research Center, High Institute for Education and Research in Transfusion Medicine, Tehran, Iran.

doi
10.61186/ijbc.16.4.30
چکیده

Background: Heparin-induced thrombocytopenia (HIT) is a serious immunological adverse drug reaction that rarely occurs in patients receiving heparin. The heparin-induced platelet activation (HIPA) test, a gold-standard assay for HIT, is time-consuming, challenging, and produces qualitative results. We aimed to compare the performance properties of a flow cytometry-based functional assay for HIT diagnosis with ...

کلیدواژه‌ها
Heparin-induced thrombocytopenia (HIT), Diagnosis, Flow cytometry, Functional assay