Short-term Chelating Efficacy of Deferoxamine in Iron Overloaded Rat Hepatocytes

نویسندگان
Farsinejad, Alireza ID 1
Fakharzade, Saeede ID 2
Karbasian, Mohammad Ali ID 3
Rahbar, Maryam ID 4
Kalanaky, Somaye ID 5
Keshavarz, Morteza ID 6
Mehrvar, Azim ID 7
Mehrvar, Narjes ID 8
Faranoush, Mohammad ID 9

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doi
چکیده

Abstract Background: Iron overload is a clinical consequence of repeated blood transfusions and causes significant organ damage, morbidity, and mortality in the absence of proper treatment. The primary targets of Iron chelators used for treating transfusional Iron overload are the prevention of Iron ingress into tissues and its intracellular scavenging. The ...

کلیدواژه‌ها
Deferoxamine, Iron overload, hepatocytes