FMS-like Tyrosine Kinase-3 Mutation in a Child with Standard-risk ALL and Normal Karyotype

نویسندگان
Alavi, Samin ID 1
Kaji Yazdi, Mohammad ID 2
Arzanian, Mohammad Taghi ID 3

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چکیده

FMS-like tyrosine kinase-3 is a receptor tyrosine kinase expressed by immature hematopoietic cells and is important for the normal development of stem cells and the immune system. Mutations of FMS-like tyrosine kinase-3 have been detected in about 30% of patients with acute myelogenous leukemia and a small number of patients with acute ...

کلیدواژه‌ها
FMS-like tyrosine kinase-3, mutation, acute lymphoblastic leukemia, childhood