Extracellular Immune Signatures as Prognostic Biomarkers and Liquid-Biopsy Candidates in AML
نویسندگان
1 Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. - Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
2 Student Research Committee, Islamic Azad University, Mashhad Branch, Mashhad, Iran
3 Department of Medical Genetics and Molecular Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
4 Proteomics Research Center, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. - Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
doi
چکیده
Background: Acute myeloid leukemia (AML) has poor long-term survival, necessitating robust prognostic biomarkers. While conventional markers focus on cytogenetics and mutations, immune-extracellular genes suitable for liquid biopsy remain understudied. Methods: RNA-sequencing data from 200 AML patients were analyzed from The Cancer Genome Atlas (TCGA). Univariate Cox regression identified survival-associated genes. ...
