Evaluation of Lipid Peroxidation, Antioxidant Status and Trace Elements in Red Blood Cell Concentrates during Storage

نویسندگان
Danehpash, Sara ID 1
Shirkhanloo, Hamid ID 2
Azami, Kian ID 3
Deyhim, Mohammad Reza ID 4

1 Islamic Azad University, Pharmaceutical Sciences Branch (IAUPS), Tehran, Iran

2 Research Institute of Petroleum Industry (RIPI), Tehran, Iran

3 Islamic Azad University, pharmaceutical Sciences Branch (IAUPS), Tehran, Iran

4 Blood Transfusion Research Center, High Institute for Research and Education for Transfusion Medicine, Tehran, Iran

doi
چکیده

Background: Red blood cell concentrates (RBCs) undergo biochemical and structural changes during storage, commonly referred to as the RBC storage lesion (RSL) which reduces the survival of RBCs and affect transfusion efficiency. Lipid peroxidation and oxidative damage are the most important side effect of RSL. We aimed to evaluate oxidative ...

کلیدواژه‌ها
Red blood cell concentrate, Red blood cell storage lesion, Oxidative damage, Lipid peroxidation, Antioxidant status, Trace elements