Microparticle Formation and Platelet Shrinkage in Type-I Glanzmman Thrombasthenia Platelets

نویسندگان
A, Farsinezhad ID 1
G, Toogeh ID 2
T, Hemmati ID 3
MR, Managhchi ID 4
M, Faranoush ID 5

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چکیده

Background: Activated normal platelets undergo many biochemical and morphological changes, some of which are apoptotic. Platelet derived microparticles and shrinked platelets as hallmark of platelet activation and apoptosis disperse surfaces containing procoagulant activity around injured vessels and tissues. This study was conducted to determine microparticles formation and platelet shrinkage in ...

کلیدواژه‌ها
Apoptosis, Glanzmann thrombasthenia, glycoprotein IIbIIIa, flow cytometry, microparticle