Medium and High-Dose Methotrexate-Induced Toxicity in Children with Acute Lymphoblastic Leukemia

نویسندگان
R, Zangooei ID 1
P, Vossough ID 2
F, Yazdi ID 3
M, Alebouyeh ID 4
M, Faranoush ID 5
AA, Hedayati Asl ID 6
A, Mehrvar ID 7
MR, Golpayegani ID 8
F, Azizzade ID 9

1

2

3

4

5

6

7

8

9

doi
چکیده

Background: Methotrexate has an important role in treatment of acute leukemia. We measured methotrexate level in CSF and blood of children with acute lymphoblastic leukemia to determine complications and outcomes. Materials and Methods: One hundred and twenty patients (73 male, 47 female), with mean age at diagnosis of 6.1 years ...

کلیدواژه‌ها
Leukemia, treatment, side effect, methotrexate