Association of MicroRNA-146a rs2910164 Polymorphism and Lung Cancer in Iranian Population: A Case-Control Study

نویسندگان
Seyedrezazadeh, Ensiyeh ID 1
Sharifi, Akbar ID 2
Dideban, Ali ID 3
Abd-Nikfarjam, Bahareh ID 4
Sadeghi, Morteza ID 5

1 Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2 Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran,

3 uman Genetics Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

4 Department of Immunology, School of Medicine, Qazvin University of Medical Sciences, Qazvin, Iran

5 uman Genetics Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

doi
چکیده

Background: Lung cancer is the first cause of cancer deaths worldwide. Polymorphisms in microRNAs genes affect their structure and their attachment to target genes. The purpose of the present study was to investigate the association of miR-146a rs2910164 polymorphism with the risk of non-small cell lung cancer (NSCLC) in Iranian ...

کلیدواژه‌ها
MicroRNA-146a, Polymorphism, Lung cancer, Risk factor