Expression of Proviral Integration of Moloney Virus-2 (PIM2) Gene in Patients with Acute Myeloid Leukemia and its Clinical Significance

نویسندگان
El Dahshan, Dina ID 1
Hammam, Amira ID 2
Ahmed, Aya ID 3
El Samra, Mohamed ID 4

1 Clinical Pathology Department, Faculty of Medicine, Beni-Suef University

2 Clinical Pathology Department, Faculty of Medicine, Beni-Suef University

3 Clinical Pathology Department, Faculty of Medicine, Beni-Suef University

4 Clinical Oncology Department, National Cancer Institute, Cairo University

doi
چکیده

ackground: Despite extensive research in leukemia, intracellular events leading to prolongation of cell cycle and resistance to pro-apoptotic factors are still not clearly defined. In recent years, the search for such events led to focusing on an anti-apoptotic factor, PIM-2 (Proviral integration of Moloney virus-2). The aim of the present ...

کلیدواژه‌ها
Acute myeloid leukemia PIM2 gene expression QRT-PCR, Clinical association Survival, Outcome