Metronomic Maintenance Therapy in Refractory Acute Myeloblastic Leukemia with Monosomy 7

نویسندگان
Abdolkarimi, Babak ID 1
Shahriari, Mahdi ID 2
Saleh, Fazl ID 3
Salajeghe, Pooria ID 4

1

2 pediatric hematology oncology fellowship

3

4

doi
چکیده

Patients with acute myeloblastic leukemia (AML) with monosomy 7 are a group of patients with refractory AML who have a very poor prognosis. Therefore, rationally designed new therapies, including metronomic chemotherapy regimen with histidine deacetylase inhibitors (Valporic acid, ATRA) are being investigated as potential treatments for the population of refractory cases of AML. ...

کلیدواژه‌ها
Metronomic Chemotherapy, Histone deacetylase Inhibitor, Acute Myeloblastic Leukemia, Valporic acid, All-trans retinoic acid