Microbial Allies: How Gut Microbiota Influence the Effectiveness of Immune Checkpoint Inhibitors

نویسندگان
Bashash, Davood ID 1
Azhdari Tehrani, Hamed ID 2
Yousefi, Amir-Mohammad ID 3
Salari, Sina ID 4

1 Department of Hematology and Blood Banking, School of Allied Medical Sciences Shahid Beheshti University of Medical Sciences, Tehran, Iran

2 Department of Hematology-Medical oncology, Loghman Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

3 Department of Hematology and Blood Banking, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

4 Department of Hematology-oncology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

doi
10.61186/ijbc.16.3.70
چکیده

The importance of the gut microbiota in human health and disease has been known for a long time. Current investigations involving preclinical and clinical studies have presented numerous lines of evidence indicating that gut microbiota can influence the effectiveness of cancer immunotherapies, particularly immune checkpoint inhibitors (ICIs). The gut microbiota can ...

کلیدواژه‌ها
Gut microbiota, Immunotherapy, Immune checkpoint inhibitors, ICIs, Cancer