The Positive Impact of Virulence Genes in Bacterial Pathogenicity and Colonization on the Large Bowel in Colorectal Cancer Patients

نویسندگان

1 Department of Microbiology, Islamic Azad University, North Tehran Branch, Tehran, Iran.

2 Department of Microbiology, Islamic Azad University, North Tehran Branch, Tehran, Iran.

3 Departments of Molecular Medicine, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran.

4 INRA, UMR1225, F-31076 Toulouse, France, and Universite´ de Toulouse, ENVT, UMR1225, F-31076 Toulouse, France

5 Departments of Molecular Medicine, National Institute of Genetic Engineering and Biotechnology (NIGEB), Tehran, Iran

doi
10.61186/ijbc.16.3.63
چکیده

Colorectal Cancer (CRC) is the third most common cancer around the world. Among the various factors associated with the development of CRC, bacterial infection and related toxins are considered the most critical risk factors. Several virulence genes, including fimC, cnf1, vat1, hlyD, clbB, clbN, feoA, feoB, fyuA, iroN, ireA, iutA, ...