Natural killer cell-based Immunotherapy for Solid tumors: A Comprehensive Review

نویسندگان
Awasthi, Seema ID 1
Sharma, Sonika ID 2
Singh, Vinod Kumar ID 3

1 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

2 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

3 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

doi
چکیده

Natural Killer Celle (NK) are innate immune cells with potent cytotoxic activity against tumor cells, making them attractive candidates for cancer immunotherapy. While NK cell-based therapies have shown promise in hematologic malignancies, their efficacy against solid tumors remains challenging due to the immunosuppressive tumor microenvironment (TME) and limited NK cell ...

کلیدواژه‌ها
Natural Killer (NK) Cells, Adoptive NK Cell Transfer, Tumor Microenvironment, Immunosuppressive Factors