Zinc Sulphate for Prevention of Breast Cancer Radiation Therapy-Induced Dermatitis: A Three-arm Triple-blinded Randomized Clinical Trial

نویسندگان
Ilaghi, Mehran ID 1
Eghbalian, Mostafa ID 2
Aflatoonian, Sarah ID 3
Shamsi, Sara ID 4
Yazdani, Samira ID 5
Bahador, Maryam ID 6

1 Institute of Neuropharmacology, Kerman Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran

2 Department of Epidemiology and Biostatistics, Faculty of Public Health, Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran

3 Department of Radiation Oncology, Kerman University of Medical Sciences, Kerman, Iran.

4 Department of Radiation Oncology, Kerman University of Medical Sciences, Kerman, Iran.

5 Department of Radiation Oncology, Kerman University of Medical Sciences, Kerman, Iran.

6 Department Of Radiation Oncology, Kerman University of Medical Sciences, Kerman, Iran

doi
چکیده

Background: Radiation therapy (RT)-induced dermatitis is a common side effect in breast cancer patients that impacts quality of life and treatment compliance. Although zinc sulphate has shown potential for reducing skin lesions in preclinical studies, clinical evidence is still limited. Methods: In this three-arm triple-blinded randomized trial, 180 breast cancer patients ...

کلیدواژه‌ها
Radiation Therapy, Dermatitis, Skin Toxicity, Breast Cancer, Zinc Sulphate, Clinical Trial