Efficacy and Safety of Ensartinibin ALK-positive Non-Small Cell Lung Cancer Patients: A Systematic Review and Meta-analysis

نویسندگان
Kumar Singh, Vinod ID 1
Awasthi, Seema ID 2
Haria, Jigar ID 3
Singh, Prithpal ID 4

1 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

2 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

3 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

4 TMMC&RC, Teerthanker Mahaveer University, Moradabad, UP, India.

doi
چکیده

Background: NSCLC accounts for a significant proportion of global cancer mortality, with ALK-positive NSCLC constituting approximately 9% of cases. Ensartinib has demonstrated promising systemic and central CNS efficacy in clinical trials. Methods: A systematic review and meta-analysis were performed following PRISMA guidelines, using PubMed, Web of Science, Cochrane, and Scopus databases. RCTs ...

کلیدواژه‌ها
NSCLC, Immunotherapy, Biomarkers, EGFR, Metastasis