Biology and Treatment of Hemophagocytic Lymphohistiocytosis
نویسندگان
1 University Medical Center, Department of Pediatric Hematology and Oncology, Hamburg, Germany
doi
چکیده
Hemophagocytic lymphohistocytosis (HLH) is a hyperinflammatory syndrome that occurs at all ages and is characterized by high levels of cytokines, secreted by activated T-lymphocytes and macrophages. All symptoms and laboratory changes can be explained by organ infiltration by these cells and hypercytokinemia. HLH occurs as an inherited form (genetic, primary HLH) ...