Ikaros (IKZF1): From Normal Hematopoiesis to Hematologic Malignancies

نویسندگان

1 Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, 1411718541, Iran

2 AJA Cancer Epidemiology Research and Treatment Center (AJA- CERTC), AJA University of Medical Sciences, Tehran, 1411718541, Iran

3 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, AJA University of Medical Sciences, Tehran, 1411718541, Iran

4 Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, 1411718541, Iran

5 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, AJA University of Medical Sciences, Tehran, 1411718541, Iran

doi
10.61186/ijbc.16.1.21
چکیده

Ikaros zinc finger (IKZF) transcription factors, part of the Krüppel family, have a significant role in the physiological development of immune cells. Ikaros, which is encoded by IKZF1, is a well-researched IKZF transcription factor that specifically impacts the growth and differentiation of lymphocytes. It interacts with various nuclear factors, functioning as either ...

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