Ikaros (IKZF1): From Normal Hematopoiesis to Hematologic Malignancies
نویسندگان
1 Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, 1411718541, Iran
2 AJA Cancer Epidemiology Research and Treatment Center (AJA- CERTC), AJA University of Medical Sciences, Tehran, 1411718541, Iran
3 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, AJA University of Medical Sciences, Tehran, 1411718541, Iran
4 Medical Biotechnology Research Center, AJA University of Medical Sciences, Tehran, 1411718541, Iran
5 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, AJA University of Medical Sciences, Tehran, 1411718541, Iran
doi
10.61186/ijbc.16.1.21چکیده
Ikaros zinc finger (IKZF) transcription factors, part of the Krüppel family, have a significant role in the physiological development of immune cells. Ikaros, which is encoded by IKZF1, is a well-researched IKZF transcription factor that specifically impacts the growth and differentiation of lymphocytes. It interacts with various nuclear factors, functioning as either ...