Guideline for the Diagnosis and Management of Growth and Puberty Disorders in Patients with Transfusion-Dependent Thalassemia
نویسندگان
1 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
2 Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
3 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
4 Pediatric Growth and Development Research Center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
5 Pediatric Growth and Development Research Center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
6 Pediatric Growth and Development Research Center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
7 Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
8 2 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
9 Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
10 Pediatric Growth and Development Research Center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran
11 Pediatric Growth and Development Research center, Institute of Endocrinology Iran University of Medical Sciences Tehran Iran.
doi
10.61186/ijbc.16.1.43چکیده
ntroduction: Thalassemia, particularly α and β types, are characterized by mutations causing varied clinical manifestations such as anemia, skeletal deformities, and iron accumulation. Patients with transfusion-dependent thalassemia (TDTs) often face growth and puberty complications, which are influenced by the disease’s type and severity. These disruptions not only result from chronic ...