Docosahexaenoic Acid (DHA) Impairs Docetaxel-Induced Up-regulation of miR-30a-5p and miR-126-5p Tumor Suppressors in Gastric Cancer Cell Line

نویسندگان
Shekari, Najibeh ID 1
Baradaran, Behzad ID 2
Abbasi-Kenarsari, Hajar ID 3
Kazemi, Tohid ID 4

1 Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

2 Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran

3 Department of Immunology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Department of Immunology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran

doi
10.61186/ijbc.16.1.89
چکیده

Objective: Owing to the synergistic effects of omega-3 fatty acids with chemotherapeutic agents in boosting response rates in gastric cancer (GC) patients, they became a promising addition to cancer therapy. Due to microRNAs (miRNAs) involvement in various cellular functions, their alterations in response to therapeutic interventions can offer insight into the ...

کلیدواژه‌ها
Docetaxel, Docosahexaenoic acid, microRNA-30a-5p, microRNA-126-5p, Gastric cancer