Chemokine-guided Stem Cell Migration for Retinal Regeneration: A Systematic Review

نویسندگان
Singh, Vinod Kumar ID 1
Matreja, Prithpal Singh ID 2
Chander, Ashish ID 3
Sharma, Sonika ID 4

1 Teerthanker Mahaveer University, Teerthanker Mahaveer Medical College & Research Centre (TMMC & RC), Moradabad, Uttar Pradesh, India.

2 Teerthanker Mahaveer University, Teerthanker Mahaveer Medical College & Research Centre (TMMC & RC), Moradabad, Uttar Pradesh, India.

3 Teerthanker Mahaveer University, Teerthanker Mahaveer Medical College & Research Centre (TMMC & RC), Moradabad, Uttar Pradesh, India.

4 Teerthanker Mahaveer University, Teerthanker Mahaveer Medical College & Research Centre (TMMC & RC), Moradabad, Uttar Pradesh, India.

doi
10.61882/ijbc.17.3.26
چکیده

Background: Retinal degeneration remains one of the predominant causes of blindness, with extremely low regenerative capacity in the mammalian retina. Stem cell-based therapy is a highly promising approach for retinal regeneration, but efficient stem cell migration and integration are significant challenges. This systematic review aimed to discuss chemokine-directed stem cell migration ...

کلیدواژه‌ها
Chemokines, SDF-1/CXCL12, PI3K/Akt pathway, JAK-STAT pathway