Effects of Metformin on Leukemia: Biological Mechanisms, Targets, and Treatment Possibilities
نویسندگان
1 National Institute of Genetic Engineering and Biotechnology, Tehran, Iran.
2 Islamic Azad University،Science and Research Branch, Tehran, Iran.
doi
10.61882/ijbc.17.3.35چکیده
Metformin is a widely prescribed medication for managing diabetes, but it also affects cancer cell metabolism through both direct and indirect mechanisms. Cancer cells often divide rapidly, and this quick division, along with metabolic changes, increases intracellular free radicals and inhibits the enzyme hexokinase. This inhibition prevents the conversion of glucose ...
