Efficacy and Challenges of Pediatric Cord Blood Transplantation: Insights from a Retrospective Single-Center Study

نویسندگان
Shamsian, Bibi Shahin ID 1
Zeinali, Vahide ID 2
Sayad, Arezou ID 3
Momtazmanesh, Nader ID 4
Kamfar, Sharareh ID 5

1 Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

2 Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

3 Genomic Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

4 Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

5 Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children’s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran

doi
چکیده

Background: Umbilical cord blood transplantation (UCBT) serves as a valuable alternative for pediatric patients without matched donors, particularly in urgent situations where timely transplantation is critical. While UCBT offers immunological benefits and broader donor availability, its clinical outcomes remain inconsistent, especially in non-malignant hematologic disorders. Objective: To evaluate clinical outcomes of ...

کلیدواژه‌ها
Umbilical cord blood transplantation, Graft-versus-host disease, HLA matching, Neutrophil engraftment, Graft failure