The prevalence of Lupus Anticoagulant in Iranian children and adolescents; Current status and literature review of diagnosis

نویسندگان

1 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran

2 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

3 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Tehran, Iran.

doi
10.61186/ijbc.15.4.262
چکیده

Background: Lupus anticoagulant (LAC) is an acquired IgG or IgM autoimmune antibody against platelet membrane phospholipids. LAC is an important cause of aPTT prolongation in children. We determined the prevalence of LA-positive results in ≤ 18 years patients referred to the Iranian Blood Transfusion Organization (IBTO) special reference coagulation laboratory. ...

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