Guideline for the diagnosis and treatment of diabetes mellitus in patients with transfusion-dependent thalassemia
نویسندگان
1 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
2 Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
3 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran
4 Pediatric Growth and Development Research Center, Iran University of medical sciences, Tehran-Iran
5 Pediatric Growth and Development Research Center, Iran University of medical sciences, Tehran-Iran
6 Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran
7 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
8 Pediatric Growth and Development Research Center, Iran University of medical sciences, Tehran-Iran
9 Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran
10 Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran
11 Pediatric Growth and Development Research Center, Iran University of medical sciences, Tehran-Iran
12 Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran-Iran
13 Endocrine Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Sciences (IUMS), Tehran, Iran.
doi
10.61186/ijbc.15.4.293چکیده
Thalassemia major hemoglobinopathy requires regular blood transfusions, often leading to iron overload due to repeated transfusions and increased intestinal iron absorption. The association between thalassemia major and metabolic complications, including diabetes and metabolic syndrome, has been recognized due to iron overload, insulin secretion impairment, insulin resistance, hepatic dysfunction, and other ...