Association between Cytochrome P450 2C19 Gene Polymorphisms and Hematological Malignancies in an Iranian Population
نویسندگان
1 Molecular Medicine Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran
2 Virtual University of Medical Sciences, Tehran, Iran
3 Department of Clinical Pharmacy, School of Pharmacy, Alborz University of Medical Sciences, Karaj, Iran
4 Research Center for Rational Use of Drugs, Tehran University of Medical Sciences, Tehran, Iran
doi
چکیده
Background: Cytochrome P450 2C19 (CYP2C19) is widely involved in the metabolism of some medications. On the other hand, recent studies have shown the contribution of the CYP2C19 polymorphisms to different malignancies. We aimed to investigate the association between CYP2C19 polymorphism and occurrence of hematological malignancies by comparing the phenotype distribution ...
