Detection Of 11q23 Gene Rearrangement In Children With Acute Lymphoblastic Leukemia And Its Association With Demographic Data and Response To Initial Chemotherapy On The Seventh Day Of Induction

نویسندگان
A, Alghasi ID 1
M, Pedram ID 2
F, Salari ID 3
A, Aminasnafi ID 4
L, Moeinzadeh ID 5
N, Saki ID 6
K, Jaseb ID 7
H, Yousefi ID 8
A, Saki Malehi ID 9
F, Noroozi ID 10

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چکیده

Background: Acute lymphoblastic leukemia (ALL) is the most common form of childhood cancer leading to cancer-related death in children. Most infants with ALL harbor recurring structural chromosomal rearrangements that are important initiating events in leukemogenesis but are insufficient to explain the biology and heterogeneity of the disease. Mixed-lineage leukemia-rearrangement (MLL-rearrangement) ...

کلیدواژه‌ها
Acute lymphoblastic leukemia, 11q23 translocation, Cytogenetic, Infant acute lymphoblastic leukemia, prognosis, Induction failure