Over expression of Nrf2 in Umbilical Cord-derived Mesenchymal Stem Cells Up regulates Cytoprotective Genes, TXNRD1 and GCLC

نویسندگان
F, Amiri ID 1
M, Habibi Roudkenar ID 2
H, Mehrabi Habibabadi ID 3
E, Moslemi ID 4
M, Jalili ID 5

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چکیده

Background: Mesenchymal stem cells (MSCs) are ideal cells for cell and gene therapy. However, the low survival of MSCs after transplantation has limited their applications. We aimed to evaluate the expression of cytoprotective genes including NQO1, TXNRD1, HO-1, GCLC following the over expression of Nrf2 in umbilical cord-derived MSCs (UC-MSCs). ...

کلیدواژه‌ها
Mesenchymal Stem Cells, Over-expression, Nrf2, TXNRD1, GCLC Educational games, Computer games, Self-Efficacy, Hemophilia.