The Effect of Hydration Therapy with and without Magnesium Sulfate on Prevention of Cisplatin-Induced Nephrotoxicity

نویسندگان

1 Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran

2 Associate Professor, Department of Hematology and Oncology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

3 Acquired Immunodeficiency research Centre, Isfahan University of Medical Sciences, Isfahan, Iran

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چکیده

Background: Cisplatin is an antineoplastic agent used to treat many malignancies; however, the main side effect of cisplatin is nephrotoxicity. The aim of this study was to evaluate the effect of hydration therapy with and without magnesium on prevention of cisplatin-induced nephrotoxicity. Methods: This retrospective study was performed on 46 ...