Thrombotic Thrombocytopenic Purpura: Diagnosis and Treatment

نویسندگان
Nam Avar Jahromi, Faride ID 1
Dehghani, Hossein ID 2
Tamaddon, Gholamhossein ID 3
Saeidnia, Mohammadreza ID 4
Vaziee, Elnaz ID 5
Mahmoodzade, Amir ID 6

1 Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran

2 Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran

3 Diagnostic Laboratory Sciences and Technology Research Center, School of Paramedical Sciences, Shiraz University of Medical Sciences, Shiraz, Iran

4 Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran

5 Department of Hematology, School of Paramedical, Shiraz University of Medical Sciences, Shiraz, Iran

6 Medical Biology Research Center, Health Technology Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran

doi
چکیده

Thrombotic Thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathic disease, associated with thrombocytopenia and hemolytic anemia. It is caused by an enzymatic dysfunction responsible in cleavage of blood clotting factors. In this study we have tried to review the available approaches in diagnoses of the disease as well as treatment strategies. ...

کلیدواژه‌ها
Thrombotic thrombocytopenic purpura, Diagnosis, Gene therapy