Acute Lymphoblastic Leukemia Switch Lineage upon Relapse to Acute Bilineage Leukemia: A Case Report

نویسندگان
Hosseini, Sayyideh Forough ID 1
Mehrzad, Valiollah ID 2
Nematollahi, Pardis ID 3
Emami, Anahita ID 4

1 Hematology Division of Internal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran

2 Hematology Division of Internal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran

3 Pathology Department, OMID Professional Hospital, Isfahan University of Medical Science

4 Hematology Division of Internal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran

doi
چکیده

Although acute leukemia commonly relapses in adults, the conversion of leukemic cell lineage (lymphoid or myeloid) upon relapse has rarely taken place. “Lineage switch” is a term widely used to define the leukemic lineage transformation as assessed by morphology, cytochemistry, and immunophenotyping from diagnosis to relapse. In most lineage switch cases, ...

کلیدواژه‌ها
Acute lymphoblastic leukemia (ALL), Lineage switch, Mixed-phenotype acute leukemias (MPALs), Acute bilineage leukemia