Quality of life in Iranian patients with head‑and‑neck cancer

نویسندگان

1 DDS. MSc. Member of Kerman Social Determinants on Oral Health Research Center, Kerman University of Medical Sciences, Kerman, Iran, Professor of Oral Medicine, Department of Oral Medicine, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

2 Department of Oral Medicine, Dental School, Yazd University of Medical Sciences, Yazd, Iran

3 DDS. MSc. Member of Kerman Dental and Oral Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran, Associate Professor of Oral Medicine, Department of Oral Medicine, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

4 DDS. MSc. Member of Kerman Dental and Oral Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran, Associate Professor of Oral Medicine, Department of Oral Medicine, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

5 DDS, Dentist, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran

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چکیده

BACKGROUND: The goal of treating cancer patients is to cure the patients and improve their qualityof life (QoL) during their illness. The aim of this research was to assess the QoL in Iranian patientswith head‑and‑neck cancer by European Organization for Research and Treatment of Cancer Qualityof Life Questionnaire‑Head and Neck 35 (EORTC QLQ‑H&N35) and University of Washington Qualityof Life Questionnaire (UW‑QoL).MATERIALS AND METHODS: In this cross‑sectional study, Iranian variation of EORTC QLQ‑H&N35and UW‑QoL questionnaires was administered to 210 patients with head‑and‑neck cancer. Patientswho visited the Department of Oncology at Omid Hospital in Isfahan, Shafa Hospital in Kerman,and Emam Khomeini Hospital in Tehran were selected. Kruskal–Wallis test, general linear modelmultivariate of variance, multiple regression models, and SPSS version 21 were used for statisticalanalysis.RESULTS: In the present research work, 210 patients with cancer in head and neck were underinvestigation, such that 128 patients (61%) were male and 82 patients (39%) were female. Onlythe patients with laryngeal cancer scored worse for dyspnea according to the scores from UW‑QoLquestionnaires. There were statistically significant differences for pain, swallowing, social eating,social contact, speech, taste/smell, and trismus based on the QLQ‑H&N35. Lower QoL was observedin patients with advanced (Stage III + IV) tumors and treated with radiotherapy plus surgical method.CONCLUSION: The study showed that quality of life differs due to location of tumor, stage of cancer,and treatment type.

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