One-pot, clean and energy efficient synthesis of dibenzo[b,f][1,4]oxazepine derivatives promoted by ultrasound
نویسندگان
1 Department of Science, Payame Noor University (PNU), PO Box.,19395-4697, Tehran, Iran
2 Department of Science, Payame Noor University (PNU), PO Box.,19395-4697, Tehran, Iran
3 Chemistry and Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran
4 Department of Chemistry, Tehran Science and Research Branch, Islamic Azad University, Tehran, Iran
5 Chemistry and Chemical Engineering Research Center of Iran, PO Box 14335-186, Tehran, Iran
doi
10.22631/ajgc.2017.95751.1018چکیده
In the present study, a variety of dibenzo [b,f][1,4] oxazepine derivatives was successfully synthesized in good yields under ultrasonic irradiation as an environmental friendly technique. This one-pot method is practically reliable, mild, catalyst-free, and inexpensive. Ultrasonic irradiation on the reaction mixture leads to fine emulsion between the reactants and violent collapses of a lot of cavitation bubbles in less than a microsecond releases extreme heat, leading to cross the activation energy barrier. In the absence of ultrasonic irradiation, a trace amount of the product was formed after 50 min. The superiority of the ultrasound irradiation over other methods in the synthesis of dibenzo [b,f][1,4] oxazepine derivatives is its low reaction temperature and operational simplicity in approximately same yields.
