Memory and Learning Improvement by Resveratrol and Probiotics via the ‎Gut-Brain Axis and Antioxidant Activity in Diabetic Rats

نویسندگان
Tayebinia, Heidar ID 1
Komaki, Alireza ID 2
Abbasi-Oshaghi‎, Ebrahim ID 3
Mashayekhi, Sodabeh ‎ ID 4
Khodadadi, Iraj ID 5
Mirzaei, Fatemeh ID 6

1 Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran

2 Neurophysiology Research Centre, Hamadan University of Medical Sciences, Hamadan, Iran

3 Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran

4 Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran

5 Department of Clinical Biochemistry, Hamadan University of Medical Sciences, Hamadan, Iran

6 Department of Anatomy, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran

doi
10.32592/ajnpp.2021.8.2.107
چکیده

Background and Objectives: Diabetes affects the central nervous system associated with cognition, especially memory and learning. The present study aimed to investigate the effects of probiotics (living microorganisms that provide health benefits) and resveratrol (a polyphenol with potential antioxidant activity) combination on oxidative stress, glucagon-like peptide-1 (GLP-1), memory, and learning ...

کلیدواژه‌ها
Diabetes, Glucagon-like peptide-1, Memory and Learning, Oxidative Stress Probiotics, Resveratrol