Effects of Intracerebroventricular Micro-injection of Kaempferol on Anxiety: Possible GABAergic Mechanism Involved
نویسندگان
1 Department of Physiology, Neurophysiology Research Center, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
2 Department of Physiology, Neurophysiology Research Center, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
3 Department of Physiology, Neurophysiology Research Center, Faculty of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran
4 Department of Pharmacology and Toxicology, Faculty of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran
doi
10.32592/ajnpp.2021.8.2.108چکیده
Background and Objectives: Kaempferol (KM) is one of the most important plants with neuroprotection and analgesic effects. In addition, bicuculline (BIC) is a competitive antagonist of the GABAA ionotropic receptor (the most important targets of benzodiazepines and other anxiety suppressants). In this study, intracerebroventricular microinjection of KM on anxiety and its ...
