Intra-ventromedial Hypothalamus Blockade of Dopamine Type 2 Receptors by Sulpiride Ameliorates the Fertility-Disrupting Effects of Morphine in Female Wistar Rats

نویسندگان

1 Department of Biology, Faculty of Basic Sciences, Shahed University, Tehran, Iran

2 Department of Biology, Faculty of Basic Sciences, Shahed University, Tehran, Iran

3 Neurophysiology Research Renter, Shahed University, Tehran, Iran

doi
10.32592/ajnpp.2024.11.4.1.173
چکیده

Background and Objective: Polycystic ovary syndrome (PCOS) is a reproductive disorder that causes infertility. Morphine, when injected into the ventromedial hypothalamus (VMH), is effective in inducing PCO, but the mechanism of this effect, particularly concerning dopamine (DA), remains unclear. The study aims to understand how DA and its receptors contribute to ...