Acute and Chronic Effects of 3-4, Methylenedioxymethamphetamine on Pyramidal Cells of Hippocampus

نویسندگان
Bakhtiar Hesam Shariati, Mohamad ID 1
Mirzaei, Fatemeh ID 2
Soleimani Asl, Sara ID 3
Mosavi, Leila ID 4
Sohrabi, Maryam ID 5

1 Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, IR Iran

2 Department of Anatomy, Hamadan University of Medical Sciences, Hamadan, IR Iran

3 Research Center for Behavioral Disorders and Substance Abuse, Hamadan University of Medical Sciences, Hamadan, IR Iran

4 Department of Pathology, Hamadan University of Medical Sciences, Hamadan, IR Iran

5 Department of Anatomy, Hamadan University of Medical Sciences, Hamadan, IR Iran

doi
10.17795/ajnpp-21812
چکیده

Background: Ecstasy or 3-4, methylenedioxymethamphetamine (MDMA), as an amphetamine derivate, could lead to learning and memory impairment. Objectives: As the hippocampus is responsible for learning and memory, herein we evaluated acute and chronic effects of MDMA on the structure of the hippocampus. Materials and Methods: Male Wistar rats (200-250 g) received single or ...

کلیدواژه‌ها
Methylenedioxymethamphetamine, Hippocampus, Cell Death