Interaction Between L-Type Calcium Channels and Antagonist of Cannabinoid System on Anxiety in Male Rat

نویسندگان
Komaki, Alireza ID 1
Haghgooyan, Aezam ID 2
Shahidi, Siamak ID 3
Sarihi, Abdolrahman ID 4
Saleh, Iraj ID 5

1 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

2 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

3 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

4 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

5 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

doi
10.17795/ajnpp-24450
چکیده

Background: The elevated plus-maze (EPM) has been broadly used to investigate anxiolytic and anxiogenic compounds. There is little information about the effect of interaction between calcium channels and cannabinoid system on the phenomenon of anxiety. Objectives: This study aimed to examine the effects of acute and chronic coadministration of AM251, as cannabinoid ...

کلیدواژه‌ها
Verapamil, L-Type Calcium Channels, AM251, Rat, Anxiety