Impact of Intrapreneurial Amniotic Mesenchymal Stem Cells (MSC)-conditioned Medium on Spinal Calcitonin Gene-related peptide (CGRP) in Peripheral Neuropathy Models

نویسندگان
Shahrezaei, Aidin ID 1
Rahimi, Behnaz ID 2
Nasirinezhad, Farinaz ID 3
Sohani, Maryam ID 4

1 School of Medicine, Iran University of Medical Sciences, Tehran, Iran

2 Lois Pope Life Center, University of Miami, Miami, FL, USA

3 Department of Physiology, Iran University of Medical Sciences, Tehran, Iran - Physiology Research Center, Iran University of Medical Sciences, Tehran, Iran

4 School of Medicine, Iran University of Medical Sciences, Tehran, Iran

doi
10.53208/ajnpp.12.3.124
چکیده

Background and Objective: Neuropathic pain, characterized as a persistent ailment, presents considerable therapeutic obstacles owing to the restricted effectiveness of contemporary interventions. This study aimed to assess the therapeutic efficacy of conditioned medium (CM) derived from human amniotic membrane mesenchymal stem cells (MSCs) in mitigating neuropathic pain and regulating spinal calcitonin ...

کلیدواژه‌ها
Calcitonin gene-related peptide (CGRP) levels, Chronic constriction injury (CCI), Conditioned medium (CM), Human amniotic stem cells, Neuropathic pain