Effect of Duloxetine Acute Treatment against 3, 4 Methylenedioxymethamphetamine-Induced Cognitive Impairment and Memory Deficiency in Male Rats

نویسندگان
Hashemi Firouzi, Nasrin ID 1
Soleimani Asl, Sara ID 2
Shahidi, Siamak ID 3

1 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

2 Anatomy Department, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

3 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, Iran

doi
10.32592/ajnpp.2020.7.3.108
چکیده

Background and Aims: 3, 4- methylenedioxymethamphetamine (MDMA) is used for recreational purposes worldwide. The use of MDMA resulted in learning and memory dysfunction. Duloxetine, a serotonin/noradrenalin-reuptake inhibitor is also utilized to treat depression and anxiety. The current study aimed to evaluate the effects of duloxetine against MDMA's effect on anxiety, cognition, ...

کلیدواژه‌ها
Anxiety, 3, 4- Methylenedioxymethamphetamine (MDMA), Learning and memory, Rat