Effect of Amyloid β- Peptide on Passive Avoidance Learning in Rats: A Behavioral Study

نویسندگان
Nikkhah, Ali ID 1
Ghahremanitamadon, Fatemeh ID 2
Zargooshnia, Somayeh ID 3
Shahidi, Siamak ID 4
Soleimani Asl , Sara ID 5

1 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

2 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

3 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

4 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran

5 Neurophysiology Research Center, Hamadan University of Medical Sciences, Hamadan, IR Iran; Department of Anatomy, Hamadan University of Medical Sciences, Hamadan, IR Iran

doi
10.17795/ajnpp-18664
چکیده

Background: Alzheimer's disease (AD) is the most common form of dementia that leads to neurotoxicity. Amyloid β-peptide (Aβ) has a pivotal role in the pathogenesis of AD. Objective: Given the contradictory results of Aβ (25-35) on the memory, in the present study we have examined the effect of Aβ - induced memory ...

کلیدواژه‌ها
Alzheimer's disease, Amyloid β-peptide, Learning, Rats