Protective effect of swimming and genistein on the expression of microRNA 132, insulin growth factor 1, and brain-derived neurotrophic factor genes, as well as spatial memory, in the hippocampus of diabetic ovariectomized rats
نویسندگان
1 Department of Pharmaceutical Biotechnology, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran
2 Student Research Committee, Hamadan University of Medical Sciences, Hamadan, Iran
3 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
4 Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
5 Neurophysiology research center, Hamadan University of Medical Sciences, Hamadan, Iran
6 Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
doi
10.32592/ajnpp.2021.8.4.102چکیده
Background and Objective: The present study aimed to assess the effects of the combined use of exercise and genistein on the hippocampal expression of microRNA-132, IGF-1, and BDNF in type 2 diabetic ovariectomized rats. Materials and Methods: Wistar female rats in the weight range of 180-220 gr (n=10) were assigned to ...
