Effect of Surface Modification on Viability of L929 Cells on Zirconia Nanocomposite Substrat
نویسندگان
1 Biomaterials Research Group, Department of Materials Engineering, Isfahan University of Technology, Isfahan, Iran
2 Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
3 Dental Material Science, Head of Unit, Faculty of Dentistry, The University of Hong Kong, 4/FDental Material Science, The Prince Philip Dental Hospital, 34Hospital Road, Sai Ying Pun, Hong Kong
4 Dental Materials Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
5 Torabinejad Dental Research Center, Department of Operative Dentistry, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran
6 DepartmentofAnatomicalSciencesandMolecularBiology,SchoolofMedicine,IsfahanUniversityofMedicalSciences,Isfahan81746-73461,Iran
doi
15497چکیده
Introduction: Zirconia bioceramic can be considered for metallic replacement in dental implant applications. A proper method of surface modification may promote better osseointegration.Methods: In study evaluated viability of fibroblast cell following surface treatment. Therefore, viability L929 cells were characterized using MTT assay and scanning electron microscopy.Results: The viability assessment determined significant differences A-Y-TZP20 without surface treatment as compared to laser surface treatment (B), laser surface treatment + hydroxyapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) and control. This study demonstrated that L929 cells approximately proliferated and spread on A-Y-TZP20 nanocomposite disk in laser surface treatment(B), Laser surface treatment + hydroxiapatite-yttrium stabilized tetragonal zirconia nanocomposite coat (C) groups similar to control group.Conclusion: Laser surface treatment showed positive effect on the viability of L929 cells.
