Effects of Chlorogenic Acid on Epileptic Behavior and mRNA Expressions of Brain Derived Neurotrophic Factor in the Brain of Aged Rats

نویسندگان
Hafizi-Barjin, Zainab ID 1
Esmaeilidehaj, Mansour ID 2
Soleimani, Hossain ID 3
Rezvani, Mohammad Ebrahim ID 4
Zaremehrjerdi, Fatemeh ID 5

1 Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

2 Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

3 Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

4 Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

5 Department of Physiology, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran

doi
10.18502/ehj.v7i2.8121
چکیده

Introduction: The present study was conducted to evaluate the effect of Chlorogenic Acid (CA) and Diazepam (DZP) on epileptic complication that induced by repetitive intra-peritoneal injections of Pentylenetetrazle (PTZ) in aged rats.   Methods: Twenty-four month-old male Wistar rats (age > 12 months, 300-350 g) were divided in 4 experimental groups. ...

کلیدواژه‌ها
Aging, Rat, Epilepsy, Chlorogenic Acid, Brain Derived Neurotropic Factor