فهرست نشریات علمی دسترسی آزاد ایران

Introduction: The primary aim of surgical procedures for Hirschsprung's disease is to establish proper bowel movement without fecal incontinence, constipation and entrocolitis. In this study we evaluated short and mid-term outcomes in children with Hirschsprung's disease undergoing different surgical procedures. Method and materials:  In a prospective singe blind study, 50 children with Hirschsprung's disease were selected. Patient eligibility included age under ten years and an elective single stage Duhamel (D group) or trans- anal procedure (T group).Primary end point data collected included the development of post-operative constipation and fecal incontinency in groups. Secondary end points of study were intra-abdominal infection, anastomotic leak, wound infection and Hirschsprung associated enterocolitis . Results: Post-operative constipation persisted in 14 (56%) after 1 month in D group and in 7(28%) in T group (p =0.04).  Post –operative constipation persisted in 16 (64%) after 6 month in D group and in 10(40%) in T group (p =.08). There was no significant difference in fecal incontinency rates between groups. Conclusion: For young children with Hirschsprung's disease who scheduled for operation, we had found no clear difference in mid-term outcome.