فهرست نشریات علمی دسترسی آزاد ایران

Objective(s): This study assessed the outcome of regenerative endodontic procedures (REPs) in permanent immature necrotic teeth. Methods: This longitudinal cross-sectional study was conducted on permanent immature necrotic teeth that had undergone REPs from 2013 to 2018. The patients were contacted by phone and asked to show-up for clinical and radiographic examinations of their treated teeth. The preoperative parallel periapical (PA), 6-18-month postoperative radiographs, and clinical examination results were collected and compared. Functional presence of the respective tooth in dental arch with no need for an endodontic treatment in the follow-up sessions was considered as treatment success. Data were analyzed by paired t-test (alpha=0.05). Results: Twelve patients (N=16 teeth) met the inclusion criteria; of which, 9 (N=12 teeth) showed up for the follow-up. The mean age of patients was 15±8.44 years (range 10 to 23 years). Ten teeth had experienced trauma, and the remaining two were necrotic due to anomalies (Turner’s hypoplasia and supernumerary tooth). Six teeth had undergone REPs with calcium-enriched mixture (CEM) cement, 4 with Biodentine, and 2 with mineral trioxide aggregate (MTA). Eleven out of 12 teeth were functional with no clinical sign/symptom at 6-12, and 18-month follow-ups, and were considered as treatment success. Closure of apical opening was significant (P=0.049). Conclusion: REPs through revascularization by using CEM cement, Biodentine, and MTA can be successful and increase the chance of completion of root development in permanent immature necrotic teeth.