The effect of Carvacrol on Enterococcus faecalis as a final irrigant
نویسندگان
1 Department of Endodontics, Faculty of Dentistry/Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
2 Department of Endodontics, Faculty of Dentistry/Dental Research Center, Tehran University of Medical Sciences, Tehran, Iran.
3 Instructor of Microbiology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
4 Department of Endodontics, Dental School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
5 Student of dentistry, Dental School, Tehran University of Medical Sciences, Tehran, Iran.
doi
10.22037/iej.v4i3.1417چکیده
INTRODUCTION: Sodium hypochlorite (NaOCl) is an effective antimicrobial irrigant, however its toxic effects and deterrent odor are not ideal. Carvacrol is an edible plant extract with anti-inflammatory and anti-bacterial properties that is effective against Enterococcus (E) faecalis. The aim of this study was to evaluate Carvacrol's antibacterial efficacy against E. faecalis bacteria as a final irrigant. MATERIALS AND METHODS: Forty extracted single-rooted human teeth were utilized. After mechanical preparations, samples were randomly divided into three experimental (A, B and C) and two control groups. E. faecalis was cultured in both experimental and positive control groups. After bacterial counting in all canals, 5.25% NaOCl, 0.6% Carvacrol emulsion and MTAD were used as final irrigants in groups A, B and C respectively. Data were analyzed using Kruskal-Wallis and Mann-Whitney U tests. RESULTS: There was no meaningful difference in bacterial reduction between groups A and B; however, group C showed significantly lower efficacy compared to other groups (P<0.05). CONCLUSION: The 0.6% Carvacrol disinfects root canals effectively. It also has anti-inflammatory qualities and therefore may be an acceptable alternative for NaOCl.
